Utilizing Multiple Model Systems to Understand Facial Development and Dysmorphologies

Chair(s)

• LT

  Lisa Taneyhill, PhD

  Professor
  Animal and Avian Sciences
  University of Maryland
  College Park, Maryland, United States

Co-sponsored by the Society for Craniofacial Genetics and Developmental Biology (SCGDB)
This symposium will address current issues in understanding the developmental events that occur during craniofacial morphogenesis and how perturbation of these events leads to human facial dysmorphologies. This topic is relevant to human health, as facial differences are some of the most frequently observed among human birth difference syndromes. More importantly, while current research often utilizes model systems to understand the molecular and cellular events in facial development, too often results from one model system are used to draw conclusions on all human or model systems. The three speakers chosen utilize multiple model systems in their work, comparing the outcomes of one model system with that of another to better understand the evolutionary conservation of developmental processes and to identify those processes that are most crucial for facial development.

Presentations:

• 8:30 AM - 9:00 AM US PDT

  Chickens (in a) Coup with Mice: Leveraging Animal Models to Study Craniofacial Development and Disease
  

  Speaker: Lisa Taneyhill, PhD – University of Maryland
• 9:00 AM - 9:30 AM US PDT

  Using Xenopus and Mouse to Dissect the Role of Six1 and Six1-associated Genes in Craniofacial Birth Defects
  

  Speaker: Andre Luiz Pasqua Tavares, DDS, MS, PhD – University of Delaware
• 9:30 AM - 10:00 AM US PDT

  Modeling Craniofacial Spliceosomopathies: A Tale of Frogs and Embryonic Stem Cells
  

  Speaker: Jean-Pierre Saint-Jeannet – New York University